221 Main - Restaurant & Cocktail House
221 Main St, St Joseph
(269) 982-4000
Customers' Favorites
Parmesan Crusted Whitefish
Firecracker Shrimp
Comeback Burger
Seafood Pasta
Prime Rib Dip
Surf and Turf
Filet & Shrimp
Starter Salad
Creme Brulee
Lake Perch
Recent Reviews
The food at 221 Main is amazing. I have always LOVED every dish I’ve ordered. My very favorite dish of all is the whitefish. It’s the best I’ve ever had and I keep going back for more. Thanks to Liz, the manager, who is always incredibly kind and accommodating. You ROCK!!!! To our bartender/server tonight, Maya, THANK YOU! You did a wonderful job tonight and we thoroughly appreciate it. Way to go 221 Main!!!! We will DEFINITELY be back SOON!
Came here on 04/18/2025, but haven’t had a chance to review it until now.
Absolutely amazing dining experience—-from the food, to the service, to the atmosphere! Right off the bat, the host was very welcoming and friendly! Our wait staff was Megan J, and she too, was very friendly, with warm smile and was attentive.
To start, we had the Seared Ahi Tuna. Taste and presentation was spectacular! In fact, everything was! For drinks, my husband...
Absolutely amazing dining experience—-from the food, to the service, to the atmosphere! Right off the bat, the host was very welcoming and friendly! Our wait staff was Megan J, and she too, was very friendly, with warm smile and was attentive.
To start, we had the Seared Ahi Tuna. Taste and presentation was spectacular! In fact, everything was! For drinks, my husband...
*Edit - my wife and I also come from the food and beverage industry in Vegas. This...