Panacea CoffeeHouse, Cafe and Roastery

66 Commerce St, Waynesville
(828) 452-6200

Recent Reviews Order Online

Customers' Favorites

Quiche of the Day Meat Ham and Cheese Croissant
Wakey Wakey Sandwich with Everything Bagel
Everything Bagel with Cream Cheese
Locs and Bagel with Cream Cheese
Breakfast Sandwich
Breakfast Quiche
Cinnamon Roll
Tres Leches
Drip Coffee
Lox Bagel

Menu

Eats
Loaded Granola
Oats, walnuts pecans, almonds, pumpkin seeds, flax seeds, cranberries, blueberries, vanilla, brown sugar, cinnamon, and local sorghum syrup.
Local Lox
Cold smoked trout capers, cream cheese, lettuce tomato, and red onion served on a bagel.
Wakey Wakey
Bacon, eggs, and cheddar cheese grilled on a bagel.
Ham Sammich
Served cold on multigrain with swiss cheese, lettuce, tomato, and red onion, mayonnaise, or mustard, grilled on sourdough with swiss cheese, and preserves dusted with powdered sugar.
Its All Good
Roasted turkey, bacon, smoked ham, swiss and cheddar cheese, lettuce, tomato, onion, side of mayonnaise on toasted sourdough.
Banana Nana
Creamy peanut butter bananas and honey. Served on your choice of multigrain or sourdough toast.
Zeus Caboose
Original hummus cucumber lettuce tomato, red onion on toasted multigrain.
Mighty Wind
Roasted turkey, cheddar cheese, hummus, lettuce, and red onion. Served on Annie's multi-grain or grilled on sourdough.

Salads
Southern Sushi
Romaine lettuce, grape tomatoes, red onion, and cucumber with turkey, ham, cheddar, swiss cheese, pinwheels, bacon, and ranch dressing.
Mount Olympus Salad
Romaine lettuce, grape tomatoes, red onion, and cucumber with garlic hummus and greek feta dressing.

Drinks
Fruit Smoothies
Chai Tea Latte
White Mocha
Ultimate Mocha
Cappuccino
Cafe Latte
Iced Coffee
Espresso
Americano
Hot Chocolate
Mocha

Whole Beans-Africa
Ethiopia Yirgacheffe
Aroma floral, lemon, and chocolate. Acidity bright. Body smooth. Taste red berry, buttery, cocoa, and caramel.
Tanzania Zanzibar Peaberry
Tanzania peaberry Zanzibar is a premium blend from high-grown estates in southern Tanzania (lunji, utengule, and kanji lanji estates) and northern Tanzania (mondul, burka, ngila, and lyamungu estates). Aroma soft pipe tobacco. Acidity bright, pungent, citric. Body juicy. Taste black tea, kiwi, chocolate, lemon, blackberry.

Whole Beans-Central America
Costa Rica Tarrazu Don Roberto
Aroma full, intense sweetness. Acidity bright. Body creamy. Taste milk chocolate and citrus.
Guatemala Santa Rosa
This coffee comes from the rich volcanic soils of the Santa Rosa Valley located in the south-central region of Guatemala. The central highlands of the country are ideal for coffee cultivation due to high altitudes and rich soil from surrounding volcanoes. The aroma is very sweet with notes of ripe berries. Acidity clean finish. Body smooth and buttery. Taste caramel, dark chocolate.
Mexico Chiapas Turquesa
Aroma full, chocolate. Acidity light to medium. Body medium. Taste sweet grape and chocolate notes.

Whole Beans-South America
Colombia Supremo Huila
Colombia is the second-largest producer of coffee in the world and the largest producer of washed and Arabica coffee. They are well known for their high-quality coffee and about half of their exports come to the united states. The supremo grade represents the highest possible; the small, less dense beans and peaberries have been removed. Aroma sweet. Acidity medium, not overly dry. Body medium to light. Taste chocolate notes, balanced and clean.
Brazil Oberon
Brazil Oberon is a 100 percent cerrado blend that consistently captures the qualities this region is celebrated for a creamy body, sweet chocolate, citric notes, and light acidity. It's a profile that has been carefully established over time. Aroma caramel and sugar. Acidity light. Body full and round. Taste chocolate, nuts, fruity finish.
Peru La Florida Fair Trade Organic
Aroma floral. Acidity medium, citrus. Body full and creamy. Taste sweet, chocolatey, floral.

Whole Beans-Asia and Pacific Island
Sumatra Mandheling Organic
Aroma clean earth, lemon, and cedar. Acidity bright citrus. Body full. Taste herbal, earthy, and woody.

Whole Beans-Espresso
Panacea Espresso Blend
Our signature blend is perfect for espresso shots as well brewed hot or iced coffee. This is the same recipe we developed when we opened 17 years ago and we still love it. Aroma spicy, fruit, and chocolate notes. Acidity is bright and clean. Body full and creamy. Taste earthy with hints of bittersweet chocolate.

Whole Beans-Decaf
Decaf Water Process Mexico
Water process decaffeinated coffees are free of added chemicals and processed using the cleanest water possible. Swap is also dedicated to aiding initiatives that support sustainability and the livelihoods of producers around the world. The aroma is nutty and sweet. Acidity light to medium. Body medium to full body. Taste nutty with hints of chocolate.
Colombia Supremo Huila
Colombia is the second-largest producer of coffee in the world and the largest producer of washed and Arabica coffee. They are well known for their high-quality coffee and about half of their exports come to the united states. The supremo grade represents the highest possible; the small, less dense beans and peaberries have been removed. Aroma sweet. Acidity medium, not overly dry. Body medium to light. Taste chocolate notes, balanced and clean.
Decaf Water Process Brazil
Brazil Oberon is a 100 percent cerrado blend that consistently captures the qualities this region is celebrated for a creamy body, sweet chocolate, citric notes, and light acidity. It's a profile that has been carefully established over time. Aroma caramel and sugar. Acidity light. Body full and round. Taste chocolate, nuts, fruity finish.
Decaf Water Process Sumatra
Water process decaffeinated coffees are free of added chemicals and processed using the cleanest water possible. Swap is also dedicated to aiding initiatives that support sustainability and the livelihoods of producers around the world. The aroma is earthy with ripe fruity sweetness. Acidity juicy. Body clean and well balanced. Taste cherry, peaches, and herbs.

Pick Up
Oregon Chai Tea Latte
Enjoy iced or hot when you need to find your peaceful place. Our Oregon chai tea latte is made with whole milk and comes in a 64 oz reusable jar.
Chocolate Covered Coffee Beans
Your favorite panacea perk. 5 oz. Package.
Coffee Caboose
Make your day easier with 96 ounces of freshly roasted and brewed coffee. This package includes cups, sweetener, and a half and half for 8 servings.

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Recent Reviews

Everything you want in a place like this. The outdoor and indoor seating accommodations alone were incredible but add the atmosphere, service and actual food, incredible. We got the Iced Tres Leches, White Mocha, Mornin’ Sunshine, and Wakey Wakey and loved it all. The cook on everything was perfect. We will definitely be back to try out more of their delicious food.
March 2026
This is the perfect spot for a cup of coffee and a light breakfast. The inside is spacious and outside are picnic tables by a creek. The staff are friendly and helpful. Dogs are welcome outside.
March 2026
Great cafe in an old industrial warehouse, right along the river. The coffee is amazing and they have good food and pastries too. The back patio area is right along a little river and is a great spot to relax and enjoy your coffee. If you’re there later in the day, they are right beside a great brewery.
January 2026

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Panacea CoffeeHouse, Cafe and Roastery

66 Commerce St, Waynesville, NC 28786
(828) 452-6200