Rx Chicken and Oysters

421 Castle St, Wilmington
(910) 399-3080

Recent Reviews

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Julie Michael Hesson

First time visit for brunch. All of our dishes were so delicious. I had the BEST shrimp and grits I’ve ever had! Highly recommend

Dawn Dykstra

We were on vacation and decided to try this restaurant because our adult son was craving raw oysters. The atmosphere is cool/eclectic and welcoming. If I had 1 complaint it was that it was very loud in there. We were there on a Friday night and the restaurant was packed so I didn't mind at all but if you are going for a quiet dinner, maybe go on a weeknight😁 We had a reservation so we were seated immediately. Our server came to our table promptly to take our drink orders. I ordered the cocktail that was a special that night and it was blueberry simple syrup with elderflower liqueur and proseco. It was delicious and refreshing without being overly strong or sweet. For appetizers we got blue crab dip for my husband and I to share and our adult son got the Lucy Bea oysters. He said they were the best oysters he has ever had, very fresh and clean tasting with the flavor of the sea. They were fantastic. Our dinners were super good with my husband getting the shrimp and grits which was rich and decadent. I got the 1/2 fried chicken which was so crunchy and dark with flavor but moist and juicy on the inside. My sides were mac&cheese and small delicious flaky buttery biscuits. Our son got the chili cheeseburger. All of the food was delicious. I'm sure the fresh caught fish is great but we are not big seafood eaters. Our desserts were fabulous too. My husband and I split the bread pudding which had large crusty/crispy bread chunks which were tender on the inside and had a caramel and whipped cream😋 Our son got the blueberry cobbler with soft serve ice cream. They were both so amazing! I would never hesitate to come and enjoy the food again the next time we are in Wilmington!

James Inabinet

Great experience with 2 adults and 2 small kids. Food was great (crab cakes and fried shrimp were very fresh)! Mac N Cheese was cheesy and had a surprising garlic flavor which worked well. Overall, great way to cap our Wilmington vacation!

Ollie Corser

Nice upscale restaurant. Delicious.

Thomas Carter

One of my favorite places. Lucy B's are probably the best oysters I've had

Latisha Jeffers

After a dud of a seafood meal the previous night, we were looking for a redemption meal. We found it at Rx Chicken & Oysters! The food is sustainable, locally sourced, and outstanding! Many places tout the “sea to table,” but few actually give you food that truly tastes like It. Rx wrote the book on it! We had the spiny lobster tail hush puppies, skillet corn bread, grouper with spiny lobster tail rice and heirloom tomato reduction, grunt with grits, seasonal vegetables and citrus and herb butter, brownie with soft serve, and blueberry cobbler. Everything was fresh and cooked perfectly! The fish had amazing flavor and the crust was just right. The tomato reduction had incredible flavor! The grits were delicious - a tasty nod to southern culture and paired with the fish nicely. Start to finish, the food was amazing and well worth the drive! If you’re looking for truly fresh, local seafood, visit Rx!

Randy Cook

Such a cool vibe for a restaurant that specializes in seafood and fried chicken! (Tuesdays are half price glasses of wine) oysters are fresh and delicious. Lobster hush puppies were sooo good - sorry no pics, we were starving. Ha! I had the beeliner (similar to red snapper) crispy and tasty. Crab cakes - A+. Gaby made sure we were happy. Y’all should check out this place. Owner spearfishes for lionfish off the coast - right to your table. Wow. I’ve been told to lookout online when these are in the kitchen. The kitchen wizards here are on point!

Peter Kalish

Hidden gem. We went for Sunday brunch and had a very tasty Bloody Mary and their shrimp and spiny lobster quiche (with Hollandaise sauce). That dish ranks as one of the few best meals we've ever eaten in Wilmington. First time to Rx but glad we found it because it won't be our last. Love the extra space between the tables making it a nice pace for a date. Service was top notch (thx Ellie). And very reasonable cost.

Kathy and Scott Reid

I read all of the great reviews of this place and just had to try it for a special occasion. Our daughter made reservations ahead of time and we thought the atmosphere was pretty cool when we walked in. We ordered crab dip and our meals, and the crab dip came out about 20 minutes later. The portion was small and the taste was simply okay and there were several pieces of crab shell in it. After a total of AN HOUR of waiting for our entrees, I went to the restroom and my daughter asked our server for an ETA. She checked, came back and said several tickets were ahead of us and she could bring us some deviled eggs. I came back from the restroom, and still no food. The server arrived shortly thereafter with the deviled eggs and said our order would be just a few more minutes. I asked her if she was sure about that because we had been there a looooong time and we were celebrating a special occasion and at that point, it didn't feel so special. She said she would get the manager. However, after several minutes went by without a visit from the manager, we slapped some money on the table for the crab dip and left. It was a VERY disappointing experience!!

Lee Rouse

Had a great dinner there. Oysters 🦪 Mussels Fried chicken Crab cakes Cocktails Service All were fantastic!!

Holly Pamela Cooper

Cozy atmosphere with good service and delicious food. Was 1st visit and will not be last. Grits yummy as was the shrimp and crab quiche. My friend had the crab Benedict and loved it.

Sarah Smith

This has quickly become one of our top favorites in Wilmington! We try something new each visit and introduce friends and family to the wonderful food and service.

Atmosphere: 5

Food: 5

Service: 5

Josh Massey

Our server was awesome!! Food was spectacular and it's true, the oysters are the best. Some of the best I've ever had!

Atmosphere: 5

Food: 5

Service: 5

Recommended dishes: Smoked Chevre & Gouda Mac and Cheese, Dinner, Baked Clams

Jeannie Brown

Wonderful creative dishes FRESH OYSTERS. Absolutely worth it go if you can! Will return place is clean service is excellent love the decor

Atmosphere: 5

Food: 5

Service: 5

Jon Knight (Sons of Cora)

Probably the best restaurant in Wilmington. Well crafted dishes in a great environment. The staff all seem happy and friendly. The bartender is BOSS AF. Spend the money and get here for a meal ASAP.

Atmosphere: 5

Food: 5

Service: 5

Recommended dishes: Deviled Eggs

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