2 Sisters Panini

1501 US-98, Daphne
(251) 930-1444

Recent Reviews Order Online

Customers' Favorites

Panini Turkey Sandwich
Smokey Panini
French Toast

Salads
Spinach Salad
Your choice of protein, spinach, feta cheese, cranberries, and almonds. Served with your choice of dressing.
House Salad
Your choice of protein, spring mix, cheddar, tomato, green peppers, and your choice of dressing.
GRILLED CHICKEN CAESAR
ROMAINE LETTUCE, GRILLED CHICKEN, PARMESAN CHEESEM, CROUTONS AND CAESAR SALAD DRESSING

Specials
Bacon Cheeseburger
Dressed with lettuce, tomato, onion, mustard, ketchup and mayo on a brioche bun. Served with french fries.

Sandwiches
Stuffed Turkey Sandwich
Hickory smoked black forest turkey, cream cheese, spinach, walnuts, and cranberry spread on whole wheat bread. Served cold with your choice of side and a pickle spear.
Cow Steamer Sandwich
Deluxe roast beef, vermont cheddar cheese, and horseradish sauce on ciabatta. Served with your choice of side and a pickle spear.
War Eagle Sandwich
Deluxe roast beef, vermont cheddar cheese, and horseradish sauce on ciabatta. Served with your choice of side and a pickle spear.
Just Cheesy Sandwich
Cheddar, pepper jack, Swiss cheese, lettuce, and tomato on white bread. Served with your choice of side and a pickle spear.
Irishman Sandwich
Corned beef top round, lettuce, tomato, onions, and mustard on rye. Served with your choice of side and a pickle spear.
Italian Sandwich
Hard salami, pepperoni, provolone, green peppers, and spicy mustard on ciabatta. Served with your choice of side and a pickle spear.
Kitchen Sandwich
Smoke master black forest ham, hickory smoked black forest turkey, everroast chicken, applewood smoked bacon, lettuce, tomato, and mayo on white bread. Served cold with your choice of side and a pickle spear.
Muffawhatta Sandwich
Smoke master black forest ham, salami, provolone, and olive mix on ciabatta. Served with your choice of side and a pickle spear.
The Veggie Sandwich
Provolone, cucumbers, lettuce, tomato, spinach, green peppers, and Italian dressing on wheat bread. Served cold with your choice of side and a pickle spear.

Wraps
Chicken Little Wrap
Chicken salad with grapes, cranberries, pecans, celery, onions, and mayonnaise wrapped in a white or wheat tortilla. Served with your choice of side and a pickle spear.
Runner Wrap
Hickory smoked black forest turkey, Swiss cheese, avocado, lettuce, tomato, and hummus wrapped in a white or wheat tortilla. Served with your choice of side and a pickle spear.
Strutter Wrap
Hickory smoked black forest turkey, applewood smoked bacon, avocado, lettuce, tomato, and ranch dressing wrapped in a white or wheat tortilla. Served with your choice of side and a pickle spear.
BLT WRAP
BACON, LETTUCE AND TOMATO IN A WHITE TORTILLA PANINI

Paninis
Roll Tide Panini
Corned beef top round, Swiss cheese, sauerkraut, and 1000 Island dressing on rye. Served with your choice of side and a pickle spear.
Smokey Panini
Hickory smoked black forest turkey, applewood smoked bacon, smoked gruyere cheese, onions, black olives, and spicy mustard on sourdough. Served with your choice of side and a pickle spear.
Doughboy Panini
EverRoast chicken, applewood smoked bacon, jalapeño pepper jack cheese, tomato, BBQ sauce, and ranch dressing on sourdough. Served with your choice of side and a pickle spear.
Charlie's Tuna Panini
Tuna salad, Swiss cheese, and tomato on rye. Served with your choice of side and a pickle spear.
Twitty Panini
Hickory smoked black forest turkey, applewood smoked bacon, Swiss cheese, avocado, and ranch dressing on wheat bread. Served with your choice of side and a pickle spear.

Sides
Side Potato Salad
Side of Coleslaw
Side Fresh Fruit
Side French Fries

Kid's Meals
Kid's Peanut Butter & Grape Jelly Sandwich Meal
Kid's Grilled Cheese Meal
Kid's Meat & Cheese Sandwich Meal
Kid's Meat & Cheese Wrap Meal

Desserts
Coconut Dream
"1 Slice. Coconut pudding and cream cheese mixture on a pecan crust. Topped with whipped cream, chopped pecans, and coconut flakes. "
Frosted Chocolate Brownie
1 piece. Chocolate brownie topped with chocolate buttercream frosting.
Two Sisters Cookie
"1 piece. Oatmeal cookie with crunchy Jif peanut butter and Hershey's chocolate. "
Chocolate Roulage
1 slice. Rolled chocolate cake with a homemade whipped cream filling. Coated with powdered sugar.
Dozen Assorted Cookies
12 pieces. Assorted cookies.

Beverages
16 oz. Fountain Drink
16 oz. Iced Tea
16 oz. Coffee
16.9 oz. Bottled Water

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Recent Reviews

2 Sisters Panini in Daphne, Alabama, is a cozy, locally owned café and deli that has been serving the community since 2011. Known for its fresh paninis, sandwiches, and baked goods, it offers a welcoming atmosphere perfect for breakfast or lunch.
October 2025
The Muffawatta is a unique and amazing take on a classic muffaletta. One of my favorite places on the Eastern Shore, great food that's not fast food and not too expensive. Highly recommend
August 2025
This place doesn’t allow dogs even on their patio that was kind of a bummer! The first lady at the register was very aloof maybe annoyed while I took my time reading the menu. When I got my order, the lady from the back happily fixed it she was great. Food was great though
April 2025

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2 Sisters Panini

1501 US-98, Daphne, AL 36526
(251) 930-1444