8 Best American Restaurants in Greenville

Sherman's @ South Main Restaurant American • $$
1697 S Main St, Greenville

Customers` Favorites

Fried Mozzarella Sticks
Chicken Fried Chicken
Spinach Artichoke Dip
Chicken Fried Steak
Baked Sweet Potato
Shrimp \u0026 Grits
Charcuterie Plate
Chopped Sirloin
Shrimp & Grits
Broiled Shrimp

“Great food and always run into good friends.“

4.5 Superb220 Reviews
Hot Tamale Heaven 82 East Mexican • $
1640 US-82, Greenville

Customers` Favorites

Tamales

“The Four Foodie Sisters took on the Tamale Trail in search of the best tamales. STOP RIGHT HERE, because this place is the bomb. It is only one of two places we would drive back to with more people!!! The Tamale Pie and the Fried Tamales are off the chart. Do not pass this up or miss out. The staff was AMAZING as well. Go to the 1427 Hwy 1 location because it has the full menu. We promise, you won't be disappointed. The Four Foodie Sisters know food“

4.5 Superb94 Reviews
Doe's Eat Place Steak House • $$$
502 Nelson St, Greenville

Customers` Favorites

Bone N Ribeye Fried \u0026 Broiled Shrimp Dozen Tamales
Bone N Ribeye Fried & Broiled Shrimp Dozen Tamales
Ribeye Steak and Fresh Cut Fries
Tamales with Chili Cheese
Doe's Famous Hot Tamales
Aunt Florence's Salad
Bone in Ribeye Steak
Hand Cut Fries
Bone-In Ribeye
Homemade Chili

“Everything was wonderful. I was in Greenville for work and I knew this was the original. The steak was cooked to perfection. We had great service. I got there a few minutes before my coworker so I ran down the street for a bottle of wine. (Yes, the restaurant provided a corkscrew.) I really loved the atmosphere. You if like upscale food in a dive environment then Doe's is for you. I love walking in through the kitchen!“

4.4 Superb279 Reviews
Spectators Pub & Patio Pubs • $
139 S Walnut St, Greenville

Customers` Favorites

Shrimp PO Boy with a Loaded Baked Potato
Caribbean Jerk Wings and Alfredo Pasta
Blackened Chicken Alfredo Pasta
Chardonnay Chicken Tacos
Grill Shrimp Dinner
Fried Shrimp Dinner
Grilled Shrimp
Mixture of All
Fish and Chips

“Great place to watch football! Service, food, and drinks are excellent!“

4.4 Superb121 Reviews
Hot Tamale Heaven And Grille American • $
1427 MS-1, Greenville

Customers` Favorites

Johnnie the Whaler Fish Sandwich
Hungry Man Country Fish Platter
Red Rooster Chicken Philly
Heavenly Sampler Platter
Fresh Squeezed Lemonade
Extreme Tamale Nachos
5 Flavor Pound Cake
Grande' Quesadilla
1 2 DZ of Tamales
Loaded Tamale Pie

“The Four Foodie Sisters took on the Tamale Trail in search of the best tamales. STOP RIGHT HERE, because this place is the bomb. It is only one of two places we would drive back to with more people!!! The Tamale Pie and the Fried Tamales are off the chart. Do not pass this up or miss out. The staff was AMAZING as well. Go to the 1427 Hwy 1 location because it has the full menu. We promise, you won't be disappointed. The Four Foodie Sisters know food“

4.1 Good195 Reviews
Downtown Grille Cocktail Bar • $$
525 Washington Ave, Greenville

Customers` Favorites

Southern Style Shrimp and Grits
Fried Green Tomatoes
Stuffed Mushrooms
Bread Pudding
Fried Shrimp
House Salad
Crab Cakes

“The ambiance is nice, not too loud and very cozy but upscale feeling. The service was quick, we were able to order and received our food in what felt like 15 minutes. My mom and I tried the pan seared salmon and it had a great crisp sear and was seasoned well, the rice was buttery in the best way, and the zucchini paired well with it all. My dad had the chicken and waffles and I snagged his fries which had a really tasty seasoning on them! He really enjoyed the chicken and waffles.“

4.2 Good139 Reviews
Huddle House American • $
2426 US-82, Greenville

Customers` Favorites

Kid's Buttermilk Pancake or Golden Waffle Plate
Hashbrowns All the Way with Two Eggs Combo
Pancakes w Strawberries and Whipped Cream
Waffle Platters with Bacon or Sausage
Mega Bacon and Cheese Omelet
Chocolate Chip Pancakes
Kid's Chicken Tenders
Fried Pickles Basket
Patty Melt Sandwich
Chicken Fried Steak

“On March 24, 2026, my husband, my nephew, and myself went to Huddle House for breakfast and were greeted by this very nice young lady. She gave us menus and waited for us to order. She brought our food out correctly. She constantly asked if we needed anything else. I wished I had asked her name. But silly me. She was so very cordial. I just have to shout the young lady out. Thanks for treating us the way we should have been treated.“

3.6 Good300 Reviews
Scoops Ice Cream & Grille Dessert • $$
1512 MS-1, Greenville

Customers` Favorites

Turkey and Dressing with Broccoli Cheese Caaorole
Philly Cheese Steak Sandwich and Onion Strings
Sunday Country Fried Steak
Hot Roast Beef Sandwich
Grilled Chicken Salad
Smokehouse Burger
Chili Slaw Burger
Hamburger Steak
French Fries
Steak Nachos

“Here’s the Scoop on Scoops!

It’s more than ice cream. 🍨. A sandwich shop w all of your hot and cold favorites.

A club sandwich w the meats, cheeses and bacon. Hot Philly steak (or chicken) and cheese.

BLT, chicken salad and more.

Lots of salad selection. Soups, fries, home fries, waffle fries, onion rings and strings.

Served hot, fresh and friendly.

Good scoops, milkshakes and sundaes.“

3.9 Good119 Reviews

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