12 Best American Restaurants near Murphysboro

St. Nicholas Brewing Co. MDH American • $
665 N Airport Rd, Murphysboro

Customers` Favorites

Strawberry Crush and Sunny Honey Mock Tails
Southwest Burger with Black Bean Patty
Loaded Fries Truffle First Class
100 Burger and Mac and Cheese
St Nicholas Brewing Co Glass
Steak and Brussels Sprouts
South Bound Grilled Cheese
Loaded Nachos with Chicken
Flight of Four Beers
Salmon Club Sandwich

“Last night was our first visit and it was amazing! The fries were cooked and seasoned to perfection. The French dip had the perfect crusted bun yet soft with great flavor. My son had his favorite beverage made to perfection.“

4.7 Superb125 Reviews
17th Street Barbecue Barbecue • $
32 N 17th St, Murphysboro

Customers` Favorites

Smoked Barbecue Chicken
Strawberry Shortcake
Smoked Chicken
Pulled Chicken
Pimento Cheese
Bread Pudding
Chicken Wings
BBQ and Beans
Pork Shoulder
Beef Brisket

“17th Street and Mike is a huge reason why I stepped out to start my own. He was a great man and all the people who work there are great. Without 17th Street, Southern Illinois wouldn't be known for their BBQ. Thanks for putting us on the map and inspiring all of us who want to become a BBQ staple in our communities. Your bbq nachos are my favorite thing to eat there.“

4.4 Superb192 Reviews
The Warehouse Barbeque • $$
217 N 17th St, Murphysboro

“The BBQ is always outstanding. This place literally sets the standard for all BBQ everywhere. I’ve had BBQ all over the country. Lots a great BBQ out there for sure, but there is none better than 17th Street. Even the sides are pretty good. This is where so many BBQ joints lose me is when they have terrible sides. We did order some potato skins and some fried pickles. Both were very good. There is a huge volume of fried pickles in one order. We got too much when we ordered 2 servings of them. Service is always good.“

4.1 Good15 Reviews
Midland Inn Bar & Grill • $
7570 Old Hwy 13, Murphysboro

Customers` Favorites

Crab Legs with Choice of Potato and Salad
Midland's Steak Sandwich
Pulled Pork Sandwich
Fried Pickle Spears
Fried Green Beans
Catfish Sandwich
Catfish Strips
Shrimp PO Boy
Grilled Quail
Catfish Plate

“When we asked the locals for a great place to eat that was laid back, Midland Inn always came up. After eating here twice in two days, i can tell you there is a reason for all of the recommendations. The food is incredible, the service was just as good. I must recommend the burgers. Highly recommend. We will be back.“

4.2 Good140 Reviews
Dale's Burger Shack American • $
1709 W Main St, Carbondale - 5.84 miles

Customers` Favorites

Veggie Burger and Sweet Potato Fries
Philly Cheesesteak Freshly Topped
Double Bacon Pepper Jack Cheese
Cheeseburger and Waffle Fries
The Impossible Burger
Mushroom Swiss Burger
Hamburger and Fries
Sweet Corn Nuggets
Mozzarella Sticks
Fried Green Beans

“My husband and I have gone the last 2 Saturdays and have not been disappointed! The fried chicken sandwich is a MUST try!! This is going to be a weekly trip from Marion to Carbondale until we have have concurred the whole menu!! Lol. 10 outta 10, DEFINITELY recommend!! The cheese steak and Chicago style was on point as well!! Not to mention, the hand cut fries!“

4.4 Superb153 Reviews
Mary Lou's Grill American • $
118 S Illinois Ave #5, Carbondale - 6.96 miles

Customers` Favorites

2 Eggs Toast Home Fries 1 2 Order of Biscuits and Gravy Coffee or Tea
Cheese Omelette with Side of Biscuits and Gravy
Sausage an Cheese Omelet Hash Browns an Gravy
2 Egg Breakfast with Bacon and Hash
Large Order of Biscuits and Gravy
Ham Omelette and Hash Browns
Biscuits and Sausage Gravy
Cheeseburger and Fries
Biscuits \u0026 Gravy
Hamburger and Fries

“This is one of my favorites!! The atmosphere is filled with nostalgia of celebrities that have passed through. The staff is friendly and always remember my face when I visit. (Hey Trina!!) The food is always cooked to order and delicious. I've never had to send anything back or complain. Definitely a place to try.“

4.3 Superb102 Reviews
Global Gourmet American • $$$
102 E Jackson St, Carbondale - 6.98 miles

Customers` Favorites

Chocolate Raspberry Truffle Cake
Cheese Board and Ceviche
Filet with Cheesy Mashed
Vanilla Cheesecake
Rack of Lamb Chops
Vegetarian Option
Duck & Andouille
Steak Au Poivre
Artichoke Dip
Pasta Special

“We recently celebrated a special birthday at Global Gourmet and was more than delighted with the service, food and hospitality given to us by our waiter and owner. We spent several hours there and wish we lived closer to have dinners on a regular basis.“

4.3 Superb65 Reviews
THIS ‘N’ THAT American • $
709 S Illinois Ave, Carbondale - 7.06 miles

Customers` Favorites

Fried Catfish Dinner with Cabbage and Baked Potato
Baked Potato with Hern Butter
Fried Catfish Fillet
Mac & Cheese

“Food was good! I had the fish and chicken meal. Mac and cheese was decent, green beans was fire too. I ordered some sweet potatoes that I didn’t end up getting, I ain’t trippin tho. I’m sure they’re 🔥 too . Overall I definitely recommend. Oh yeah, the mild sauce was very good as well!“

3.5 Good51 Reviews
Mase's Place Bar & Grill • $
5162 Hickory Ridge Rd, Pomona - 6.97 miles

Customers` Favorites

White Fish All You Can Eat
Appetizer Combo Platter

“Great food and atmosphere. Love your decor and patio.“

4.5 Superb77 Reviews
Underground Public House Gastropubs • $$
717 S University Ave, Carbondale - 7.13 miles

Customers` Favorites

Blackberry & Lavender Sour from Scratch Brewery
Blue Cheese Burger and Hand Cut Fries
Thee P B R -Pork Belly Reuben
Hangar Steak with Chimichurri
Grilled Salad with Salmon
Cheeseburger with Bacon
Pork Schnitzel Sandwich
Giant Bavarian Pretzel
Seasonal House Sausage
Tomahawk Pork Chops

“Absolutely amazing experience at Underground revamped! Hazel is the head chef and she is incredibly talented.

every dish she prepares is full of flavor and clearly made with passion and attention to detail. Beyond the food, she creates such a welcoming and enjoyable atmosphere that makes you want to stay all night. You can truly tell she cares about both the food and the people. Great energy, amazing service, and an unforgettable dining and cocktail experience. Highly recommend!“

4.3 Superb108 Reviews
Flame Bar And Grill Bar & Grill • $$
501 E Walnut St, Carbondale - 7.36 miles

Customers` Favorites

Lobster Mac and Cheese
Bacon Wrapped Meatloaf
Steak House Wedge
Paleo Steak Salad
Seared Ahi Tuna
Chicken Marsala
Street Pretzel
Seafood Tuscano
Tomahawk Steak
Surf and Turf

“From the moment we made the reservation, the staff at Flame Bar & Grill provided excellent service! Everyone was so welcoming and attentive throughout the evening. The food and cocktails were amazing, and Katie went above and beyond to make our birthday celebration extra special. We brought our own cake and forgot candles, but she not only found us a candle, she also surprised us with a fancy Happy Birthday sign for the cake. Truly wonderful service from the entire staff. We highly recommend for a great night out!“

4.2 Good111 Reviews
Chili's Grill & Bar Tex-Mex • $
1240 E Main St, Carbondale - 7.96 miles

Customers` Favorites

Plus Up Your Steak Seared Shrimp
Skillet Chocolate Chip Cookie
Chili's Secret Sauce Burger
Quesadilla Explosion Salad
Bottomless Tostada Chips
Bottomless Chips & Salsa
Chili's 1975 Soft Tacos
Loaded Baked Potato Soup
Grilled Chicken Fajitas
Loaded Mashed Potatoes

“We’ve drove over from Cape two times now and had excellent food and just as good service both times. The service was outstanding and everyone has been very friendly.“

3.5 Good120 Reviews

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