11 Best American Restaurants near Murphysboro

St. Nicholas Brewing Co. MDH American • $
665 N Airport Rd, Murphysboro

Customers` Favorites

Strawberry Crush and Sunny Honey Mock Tails
Southwest Burger with Black Bean Patty
Loaded Fries Truffle First Class
100 Burger and Mac and Cheese
St Nicholas Brewing Co Glass
Steak and Brussels Sprouts
South Bound Grilled Cheese
Loaded Nachos with Chicken
Flight of Four Beers
Salmon Club Sandwich

“Last night was our first visit and it was amazing! The fries were cooked and seasoned to perfection. The French dip had the perfect crusted bun yet soft with great flavor. My son had his favorite beverage made to perfection.“

4.7 Superb128 Reviews
17th Street Barbecue Barbecue • $$
32 N 17th St, Murphysboro

Customers` Favorites

Our Famous 17st Barbecue Pork
Smoked Barbecue Chicken
Strawberry Shortcake
Half Smoked Chicken
Pimento Cheese
Pulled Chicken
Chicken Wings
BBQ and Beans
Pork Shoulder
Bread Pudding

“17th Street and Mike is a huge reason why I stepped out to start my own. He was a great man and all the people who work there are great. Without 17th Street, Southern Illinois wouldn't be known for their BBQ. Thanks for putting us on the map and inspiring all of us who want to become a BBQ staple in our communities. Your bbq nachos are my favorite thing to eat there.“

4.4 Superb373 Reviews
The Warehouse Barbeque • $$
217 N 17th St, Murphysboro

“The BBQ is always outstanding. This place literally sets the standard for all BBQ everywhere. I’ve had BBQ all over the country. Lots a great BBQ out there for sure, but there is none better than 17th Street. Even the sides are pretty good. This is where so many BBQ joints lose me is when they have terrible sides. We did order some potato skins and some fried pickles. Both were very good. There is a huge volume of fried pickles in one order. We got too much when we ordered 2 servings of them. Service is always good.“

4.1 Good34 Reviews
Midland Inn Bar & Grill • $
7570 Old Hwy 13, Murphysboro

Customers` Favorites

Crab Legs with Choice of Potato and Salad
Midland's Steak Sandwich
Pulled Pork Sandwich
Fried Pickle Spears
Fried Green Beans
Catfish Sandwich
Catfish Strips
Shrimp PO Boy
Grilled Quail
Catfish Plate

“Love this place! If you’re looking for a patio moment to share with friends, lunch, family dinner, work place gathering or lunch, celebration spot, or just a place to breath with a cocktail or sweet tea~~this is Your PLACE!! Feels like family and all aspects are displayed of your local, Family owned business that 🩷’s their customers and their experiences!!“

4.2 Good306 Reviews
Dale's Burger Shack American • $
1709 W Main St, Carbondale - 5.84 miles

Customers` Favorites

Veggie Burger and Sweet Potato Fries
Philly Cheesesteak Freshly Topped
Double Bacon Pepper Jack Cheese
Cheeseburger and Waffle Fries
The Impossible Burger
Mushroom Swiss Burger
Hamburger and Fries
Sweet Corn Nuggets
Mozzarella Sticks
Fried Green Beans

“Tiny place with only 5 booths and 2 tables outside.
The food is so good, they could fill the place if it had twice the seating!
The burgers are traditional smash burgers done to perfection and there specialty fry boxes are absolutely delicious and filling!!
If you visit SIU, you have to give this diamond in the rough a try!!“

4.4 Superb169 Reviews
Mary Lou's Grill American • $
118 S Illinois Ave #5, Carbondale - 6.96 miles

Customers` Favorites

2 Eggs Toast Home Fries 1 2 Order of Biscuits and Gravy Coffee or Tea
Cheese Omelette with Side of Biscuits and Gravy
Sausage an Cheese Omelet Hash Browns an Gravy
2 Egg Breakfast with Bacon and Hash
Large Order of Biscuits and Gravy
Ham Omelette and Hash Browns
Biscuits and Sausage Gravy
Cheeseburger and Fries
Biscuits \u0026 Gravy
Hamburger and Fries

“Nice spot to get breakfast. My first day in town I showed up late and all they had left was meatloaf. I am not a meatloaf person, but it was really good. Got there early for breakfast on day 2 and was happy with everything. Cool little historical place. If Im ever in southern IL again, I'll be back.“

4.4 Superb110 Reviews
Global Gourmet American • $$$
102 E Jackson St, Carbondale - 6.98 miles

Customers` Favorites

Chocolate Raspberry Truffle Cake
Cheese Board and Ceviche
Filet with Cheesy Mashed
Vanilla Cheesecake
Rack of Lamb Chops
Vegetarian Option
Duck & Andouille
Steak Au Poivre
Artichoke Dip
Pasta Special

“We recently celebrated a special birthday at Global Gourmet and was more than delighted with the service, food and hospitality given to us by our waiter and owner. We spent several hours there and wish we lived closer to have dinners on a regular basis.“

4.2 Good59 Reviews
Mase's Place Bar & Grill • $
5162 Hickory Ridge Rd, Pomona - 6.97 miles

Customers` Favorites

White Fish All You Can Eat
Appetizer Combo Platter

“Great food and atmosphere. Love your decor and patio.“

4.6 Superb71 Reviews
Flame Bar And Grill Bar & Grill • $$
501 E Walnut St, Carbondale - 7.36 miles

Customers` Favorites

Lobster Mac and Cheese
Bacon Wrapped Meatloaf
Steak House Wedge
Paleo Steak Salad
Seared Ahi Tuna
Chicken Marsala
Street Pretzel
Seafood Tuscano
Tomahawk Steak
Surf and Turf

“We celebrated my daughter's birthday here. The food was delicious. We started with crab cakes and a baked lobster dip. Both top notch. For entrees, our group had the Risotto, Lasagna, Chicken Marsala, & Tuna entrees. We had the chocolate cake for dessert. Our server was attentive and friendly. We'll be returning!“

4.3 Superb115 Reviews
Underground Public House Gastropubs • $$
717 S University Ave, Carbondale - 7.13 miles

Customers` Favorites

Blackberry & Lavender Sour from Scratch Brewery
Blue Cheese Burger and Hand Cut Fries
Thee P B R -Pork Belly Reuben
Hangar Steak with Chimichurri
Grilled Salad with Salmon
Cheeseburger with Bacon
Pork Schnitzel Sandwich
Giant Bavarian Pretzel
Seasonal House Sausage
Tomahawk Pork Chops

“This is my very first time to make any review, And its because this place gets A+!!!. The Ownership/ Chef takes immense pride in all the ingredients and flavor concepts on the plates for the menu. I applaud this so much....Todays world more tban ever, When you go out to eat - Its so special to find this type of care and passion toward the dishes on the menu!.....now on to the service. Oncd again A+!!! The server and the bartender were fully engaged and you can just feel their pride in serving along with knowledge on the items on menu and drink options.

100% support this as a MUST in Carbondale.

Thank you for taking your business seriously in serving the consumer. I will be back always on my travels. Customer for life!!!!“

4.3 Superb110 Reviews
Chili's Grill & Bar Tex-Mex • $
1240 E Main St, Carbondale - 7.96 miles

Customers` Favorites

Plus Up Your Steak Seared Shrimp
Skillet Chocolate Chip Cookie
Chili's Secret Sauce Burger
Quesadilla Explosion Salad
Bottomless Tostada Chips
Bottomless Chips & Salsa
Chili's 1975 Soft Tacos
Loaded Baked Potato Soup
Grilled Chicken Fajitas
Loaded Mashed Potatoes

“We’ve drove over from Cape two times now and had excellent food and just as good service both times. The service was outstanding and everyone has been very friendly.“

3.6 Good127 Reviews

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